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Praziquantel

Praziquantel is an anthelmintic medicine used for two groups of worm infections: schistosomiasis and liver fluke disease. It kills the parasites rather than only relieving the symptoms they cause. Treatment is short, and the medicine comes as a tablet.

Medicine containing Praziquantel

Biltricide

Schistosomiasis, Liver Flukes

600mg

Praziquantel is the active ingredient in Biltricide, a tablet for schistosomiasis and liver flukes. You can choose from one strength and several pack sizes. You see the price per tablet for each option.

FromUS$2.34/ tabletView

Key points

  • Praziquantel is the recommended treatment for all forms of schistosomiasis.
  • It must not be used by people with ocular cysticercosis, a condition in which tapeworm cysts form in the eye.
  • The medicine begins to act within 1 to 2 hours, and its effect lasts about a day.

What praziquantel is used for

Praziquantel treats schistosomiasis, an infection caused by blood flukes, and infections caused by liver flukes, worms that live in or near the liver. Both are parasitic infestations, and the aim of treatment is to clear the worms from the body. It belongs to the antiparasitic class of medicines.

How it works

The medicine makes the parasite’s cell membrane more permeable to calcium ions. Calcium entering the worm triggers muscle contraction and then paralysis, so it can no longer hold its position in the blood vessels or tissues. Immobilised, the worm dies and is cleared by the body’s immune system.

Forms and brands

Praziquantel is supplied as a 600mg tablet under the brand Biltricide, which is listed for schistosomiasis and liver flukes. Orders are shipped from India to Malaysia in discreet packaging.

Safety

Do not take praziquantel if you have reacted to it before, or if you have ocular cysticercosis. Dizziness is common, so avoid driving or operating machinery while you are being treated. Headache and abdominal pain are frequently reported; nausea, tiredness and fever can also occur. Convulsions are a serious effect and need immediate medical attention. Alcohol interacts with this medicine, and rifampin must not be taken alongside it. Safety in children under four years old has not been established. If you are pregnant, discuss the risks and benefits with your doctor.

What the sources say

  • Praziquantel treats schistosoma and liver fluke infections, and it works by killing the worms (MedlinePlus).
  • A doctor will probably advise against taking praziquantel while you are on rifampin (MedlinePlus).
  • Breastfeeding should be avoided on the day of treatment and for 72 hours afterwards (MedlinePlus).
  • The medicine can cause heart rhythm problems; dizziness, a fast or irregular heartbeat, or fainting should prompt immediate medical advice (Mayo Clinic).

Further reading

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