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Carbamazepine

Carbamazepine is an anticonvulsant medicine taken by mouth as a tablet. It is used in epilepsy, in the sharp facial pain of trigeminal neuralgia, and as part of treatment for bipolar disorder. It acts on overexcited nerve membranes rather than on one organ system.

Medicine containing Carbamazepine

Carbamazepine

Epilepsy, Trigeminal Neuralgia, Bipolar Disorder

100 · 200 · 400mg

Carbamazepine tablets contain carbamazepine and are used for epilepsy, trigeminal neuralgia and bipolar disorder. You can choose from several strengths and pack sizes. You see the price per tablet for each option.

FromUS$0.48/ tabletView

Key points

  • Its full effect develops over one to two weeks, and each dose lasts roughly 8 to 12 hours.
  • The dose is adjusted according to age-based guidelines.
  • Pregnancy carries a high risk of birth defects, so it is used only if strictly necessary; breastfeeding is not recommended.

What carbamazepine is and what it is used for

Carbamazepine belongs to the carboxamide group of antiepileptic medicines. It is used in three areas:

How carbamazepine works

Carbamazepine stabilises hyperexcited nerve membranes. It blocks voltage-gated sodium channels, which inhibits repetitive neuronal firing and prevents nerve cells from firing in uncontrolled bursts. This dampens the overstimulated activity behind seizures and nerve pain.

Tablets and strengths

Carbamazepine comes as a tablet in 100mg, 200mg and 400mg strengths: Carbamazepine. It sits within the neurology range. Pharmacy partners in India ship orders to Malaysia in discreet packaging.

Who should not take carbamazepine

Avoid it after a hypersensitivity reaction to carbamazepine, and in atrioventricular block, a history of bone marrow depression, or porphyria. It should not be combined with MAO inhibitors. Skin rashes need monitoring, blood counts are checked regularly, and hepatic or renal problems call for caution.

Side effects and interactions

Dizziness, drowsiness, ataxia and nausea are common early effects. Fatigue, leukopenia, hyponatraemia and dry mouth can also occur. Serious reactions include aplastic anaemia, agranulocytosis, Stevens-Johnson syndrome and cardiac conduction block; each requires immediate medical attention. Grapefruit juice, warfarin, oral contraceptives and lithium are listed interactions, so tell your doctor or pharmacist about everything you take.

Further reading

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